Postoperative nonsteroidal anti-inflammatory drugs and risk of bleeding in pediatric intracapsular tonsillectomy
نویسندگان
چکیده
منابع مشابه
Postoperative nonsteroidal anti-inflammatory drugs and risk of bleeding in pediatric intracapsular tonsillectomy.
OBJECTIVES In light of current FDA guidelines on opioid use in children, we sought to determine the risk of post-tonsillectomy hemorrhage (PTH) in children who received ibuprofen with acetaminophen versus those who received narcotic with acetaminophen for postoperative pain control. METHODS This was an IRB-approved retrospective chart review of patients at a tertiary-care pediatric center. Th...
متن کاملNonsteroidal anti-inflammatory drugs and postoperative bleeding following adenotonsillectomy in pediatric patients.
OBJECTIVE To assess the effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on bleeding for pediatric adenotonsillectomy in a retrospective study, based on the common practices at 2 different tertiary care facilities. DESIGN A retrospective study. SETTING Two different tertiary care facilities. PATIENTS Children up to 16 years of age, who underwent elective adenotonsillectomy or tons...
متن کاملNonsteroidal anti-Inflammatory drugs and cardiovascular risk.
Nonsteroidal anti-inflammatory drugs (NSAID) inhibit cyclooxygenase (COX) enzymes, which exist in at least two isoforms, COX-1 and COX-2. Aspirin and older agents in this class are nonselective inhibitors of both COX-1 and COX-2. Newer agents termed "coxibs" are selective inhibitors of COX-2. Among the NSAID, only aspirin has been proven to significantly reduce cardiovascular risk, primarily th...
متن کاملNonsteroidal Anti-Inflammatory Drugs and Cardiovascular Risk
electivity toward cyclooxygenase (COX)-2 is usually dened by comparing the capacity of individual nonsteroidal nti-inflammatory drugs (NSAIDs) to inhibit in vitro or ex ivo the generation of thromboxane A2 (TXA2) through OX-1 in aggregating platelets with the capacity to inhibit rostaglandin (PG) E2 generation through COX-2, exressed in leukocytes after an inflammatory stimulus (1). his rather ...
متن کاملNonsteroidal anti-inflammatory drugs.
Non-steroidal anti-inflammatory drugs (NSAIDs) are usually defined as those agents that inhibit one or more reactions involved in the production of prostaglandins and thromboxanes, important mediators of the inflammatory process in many organs and tissues. They find use in horses in the supportive treatment of a variety of systemic states and painful musculoskeletal or soft tissue conditions. T...
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ژورنال
عنوان ژورنال: International Journal of Pediatric Otorhinolaryngology
سال: 2015
ISSN: 0165-5876
DOI: 10.1016/j.ijporl.2015.05.042